KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCSH
All Species:
30.3
Human Site:
Y465
Identified Species:
55.56
UniProt:
P14314
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14314
NP_001001329.1
528
59425
Y465
D
K
F
S
A
M
K
Y
E
Q
G
T
G
C
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542057
593
66107
Y530
D
K
F
S
A
M
K
Y
E
Q
G
T
G
C
W
Cat
Felis silvestris
Mouse
Mus musculus
O08795
521
58774
Y458
D
K
F
S
A
M
K
Y
E
Q
G
T
G
C
W
Rat
Rattus norvegicus
NP_001100276
525
59200
Y462
D
K
F
S
A
M
K
Y
E
Q
G
T
G
C
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510649
692
76488
Y506
D
K
F
S
V
M
K
Y
E
H
G
T
G
C
W
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086185
514
57354
S450
P
E
D
N
K
F
S
S
M
K
Y
E
H
G
T
Zebra Danio
Brachydanio rerio
NP_957347
529
59566
Y466
N
K
Y
L
S
M
K
Y
E
H
G
T
G
C
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609844
548
61521
Y485
K
Q
Y
S
Q
Q
K
Y
T
N
G
A
A
C
W
Honey Bee
Apis mellifera
XP_625125
493
56012
K430
P
E
G
Q
K
Y
F
K
M
K
Y
D
R
G
L
Nematode Worm
Caenorhab. elegans
NP_496073
507
58044
K445
P
E
G
N
K
Y
S
K
M
H
F
G
D
G
Q
Sea Urchin
Strong. purpuratus
XP_789169
523
60041
Y459
N
K
Y
S
L
M
M
Y
T
K
G
Q
K
C
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001146004
602
67827
F530
D
S
Y
R
V
M
H
F
S
S
G
D
K
C
W
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04924
702
79889
Y640
N
N
G
L
V
L
E
Y
E
N
G
D
Q
C
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
80.9
N.A.
86.7
85.2
N.A.
53.6
N.A.
62.3
62.3
N.A.
38.3
41.4
36.7
43.7
Protein Similarity:
100
N.A.
N.A.
83.9
N.A.
92.9
91.6
N.A.
61.9
N.A.
77
76.7
N.A.
53.2
57.9
56.4
59.4
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
86.6
N.A.
0
66.6
N.A.
40
0
0
46.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
86.6
N.A.
20
86.6
N.A.
53.3
13.3
13.3
66.6
Percent
Protein Identity:
N.A.
31.8
N.A.
N.A.
21.9
N.A.
Protein Similarity:
N.A.
48.6
N.A.
N.A.
39.8
N.A.
P-Site Identity:
N.A.
33.3
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
31
0
0
0
0
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
77
0
% C
% Asp:
47
0
8
0
0
0
0
0
0
0
0
24
8
0
0
% D
% Glu:
0
24
0
0
0
0
8
0
54
0
0
8
0
0
0
% E
% Phe:
0
0
39
0
0
8
8
8
0
0
8
0
0
0
0
% F
% Gly:
0
0
24
0
0
0
0
0
0
0
77
8
47
24
0
% G
% His:
0
0
0
0
0
0
8
0
0
24
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
54
0
0
24
0
54
16
0
24
0
0
16
0
0
% K
% Leu:
0
0
0
16
8
8
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
62
8
0
24
0
0
0
0
0
0
% M
% Asn:
24
8
0
16
0
0
0
0
0
16
0
0
0
0
0
% N
% Pro:
24
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
8
8
8
0
0
0
31
0
8
8
0
8
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
8
0
54
8
0
16
8
8
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
16
0
0
47
0
0
8
% T
% Val:
0
0
0
0
24
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
77
% W
% Tyr:
0
0
31
0
0
16
0
70
0
0
16
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _